FcgRIIIa 158V/GPI receptor expressing cell line
Technology No.
CHO cells transfected to express human FcgRIIIa of the 158V allotype on their surface as glycosyl-phosphatidylinositol-anchored molecules useful for investigation of the binding of recombinant antibodies to human Fc receptors.
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swap_vertical_circlemode_editAuthors (1)Michael R Clark
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swap_vertical_circlelibrary_booksReferences (4)
- Kathryn L Armour, Cheryl S Smith, Michael R Clark (4 February 2010), Expression of human FcgammaRIIIa as a GPI-linked molecule on CHO cells to enable measurement of human IgG binding, Journal of Immunological Methods, 354, 20-33
- Kathryn L Armour, Cheryl S Smith, Craig P Turner, Christopher M Kirton, Anthony M Wilkes, Andrew G Hadley, Cedric Ghevaert, Lorna M Williamson, Michael R Clark (28 November 2013), Low-affinity FcγR interactions can decide the fate of novel human IgG-sensitised red blood cells and platelets, European Journal of Immunology, 44, 905-914
- Kathryn L Armour, Cheryl S Smith, Natasha C Y Ip, Cara J Ellison, Christopher M Kirton, Anthony M Wilkes, Lorna M Williamson, Michael R Clark (10 October 2014), Clearance of human IgG1-sensitised red blood cells in vivo in humans relates to the in vitro properties of antibodies from alternative cell lines, PLOS One
- Alice Harrison, Zhe Liu, Schona Makweche, Kevin Maskell, Hong Qi, Geoff Hale (7 April 2012), Methods to measure the binding of therapeutic monoclonal antibodies to the human Fc receptor FcγRIII (CD16) using real time kinetic analysis and flow cytometry, Journal of Pharmaceutical and Biomedical Analysis, 63, 23-28
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swap_vertical_circlecloud_downloadSupporting documents (1)Product brochureFcgRIIIa 158V/GPI receptor expressing cell line.pdf
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